Tag: Cancer

Disorderly DNA helps cancer cells evade treatment

Each cell in the human body holds a full two meters of DNA. In order for that DNA to fit into the cell nucleus—a cozy space just one hundredth of a millimeter of space—it needs to be packed extremely tight. A new Northwestern University study has discovered that the packing of the three-dimensional genome structure,

Public insurance tied to lower cancer survival in young patients

(HealthDay)—Young, low-income patients with bone or soft tissue sarcomas have decreased overall survival (OS), regardless of disease stage at presentation, according to a study published online Dec. 15 in Cancer Medicine. Neela L. Penumarthy, M.D., from Seattle Children’s Hospital, and colleagues used data from the University of California San Francisco Cancer Registry to identify patients

Free tool simplifies cancer research

Every cell contains a vast number of proteins, each of which has a specific function, for example, as a receptor for another molecule or an enzyme that catalyzes chemical reactions. Disorders of such mechanisms can seriously affect a cell and cause diseases such as cancer, in which the sick cell functions fundamentally differently from a

Residual cancer burden after neoadjuvant therapy can accurately predict breast cancer survival

Researchers from The University of Texas MD Anderson Cancer Center today reported results from a pooled analysis of more than 5,100 breast cancer patients that found residual cancer burden (RCB) continuous index and classification were independently and strongly prognostic for all breast cancer phenotypes. The study’s results were presented by W. Fraser Symmans, M.D., professor

Metabolic adaptation ensures survival of colon cancer cells

Colon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to adapt to the lack of oxygen and nutrients inside the tumor. Statins, which are often prescribed to lower cholesterol, block this metabolic pathway and cause the cancer cells to die, as scientists from

Recruitment of miR-8080 by luteolin inhibits AR-V7 in castration-resistant prostate cancer

Prostate cancer is the most common noncutaneous malignancy in the United States and is responsible for many male deaths. The development of prostate carcinogenesis is initially androgen-dependent. However, the progression of castration-resistant prostate cancer (CRPC) following androgen deprivation therapy is a major clinical problem. Although enzalutamide and abiraterone have been approved for CRPC hormone therapy,

Study explores new tracer in prostate cancer hunt

A new study looks to move doctors and patients closer to earlier and more precise detection of recurrent prostate cancer that would clarify treatment decisions and lead to more confident courses of action and better health outcomes. A multi-center trial registry testing the use of a new imaging tracer—prostate specific membrane antigen (PSMA) – is

Immune ‘checkpoint switch-off’ enables destruction of cancer cells

A collaboration between the Griffith Institute for Drug Discovery (GRIDD) and multiple clinical research institutes has led to an exciting discovery in cancer research. The multi-disciplinary team, led by GRIDD’s Dr. Alexandre Cristino and Professor Maher Gandhi from Mater Research and including researchers from the Translational Research Institute, discovered a new mechanism in which the

Do you think I DESERVE to have incurable lung cancer?

Do you think I DESERVE to have incurable lung cancer? How one mother deals with the accusation that her terminal illness is self-inflicted having smoked 10 cigarettes a day When I first tell people I have terminal lung cancer, I’m usually met by one of three responses. Most commonly, it’s a concerned tilt of the

Herbal remedies could interfere with breast cancer treatments

Herbal remedies such as turmeric, ginseng and garlic could interfere with breast cancer treatments, doctors warn At an advanced stage of breast cancer, lesions often spread to the skin  Many patients attempt to sooth these with creams and herbal treatments But researchers based in Portugal have now said these delay wound healing And they warned