Tag: disease

Two new studies reveal that modern machine learning—a branch of artificial intelligence in which systems learn from data, identify patterns, and make decisions—may augment traditional diagnostics of kidney disease. The findings appear in an upcoming issue of JASN. Pathologists often classify various kidney diseases on the basis of visual assessments of biopsies from patients’ kidneys;

A mutation that causes a type of muscular dystrophy that affects the limbs protects against HIV-1 infection, according to a study published August 29 in the open-access journal PLOS Pathogens by Sara Rodríguez-Mora, Mayte Coiras and José Alcamí of the Instituto de Salud Carlos III in Madrid, Spain, and colleagues. As the authors noted, this

Researchers led by Duke-NUS Medical School have discovered that tryptase, an enzyme in human cells that acts like scissors to cut up nearby proteins, is responsible for blood vessel leakage in severe dengue hemorrhagic fever. The finding suggests a possible new treatment strategy using the tryptase inhibitor, nafamostat mesylate, for severe dengue disease—a potentially fatal

Survivors of childhood cancer have a higher risk of developing a range of heart disease due to cancer therapy, according to new research published in the American Heart Association’s journal Circulation. Most studies of this survivor group have focused on heart failure related to anthracyclines, a class of chemotherapy medications used to treat many types

There is only one existing vaccine for TB and it is not effective in adults. Researchers at the Centenary Institute and University of Sydney will next test their new vaccine in clinical trials with humans. Australian medical researchers from the Centenary Institute and the University of Sydney have successfully developed and tested on mice a

Vaping is widely assumed to be safer than cigarette smoking, but scientists at the University of North Carolina School of Medicine have uncovered evidence suggesting that vaping promotes the same cellular responses found in smokers who suffer with emphysema. In a study published in the American Journal of Respiratory and Critical Care Medicine, the UNC

A new study has shed light on a possible risk factor for Alzheimer’s disease in women: not having a job. Dr. Elizabeth R. Mayeda, assistant professor of epidemiology at UCLA’s Fielding School of Public Health, conducted a study on later-life cognitive health in women and found that working women showed a slower decrease in memory

An omega-6 polyunsaturated fatty acid has the potential to help fight heart disease, finds a new study by researchers at Cardiff University, in collaboration with Ben-Gurion University of the Negev. With funding from the British Heart Foundation, the team found that dihomo-gamma-linolenic acid (DGLA), an omega-6 polyunsaturated fatty acid, could halt the progression of atherosclerosis—one

The pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer’s drug that targets toxic substances released by P. gingivalis, a bacteria linked to gum disease. In a poster presented at the Alzheimer’s Association International Conference today (Wednesday, July 17), researchers provided an overview of the development of the drug, known as COR388, and

The strongest genetic risk factor for Alzheimer’s disease is the apolipoprotein E type 4 allele (ApoE ε4). Research presented by Manish Paranjpe at the 2019 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) used positron emission tomography (PET) to show that women who are ApoE ε4 carriers and already experiencing mild

Infectious proteins called prions cause a group of related, fatal and incurable neurodegenerative disorders, including bovine spongiform encephalopathy or Mad Cow disease and Creutzfeldt-Jakob disease, both of which affect humans. Chronic wasting disease or CWD, also caused by prions, has reached the point of a global epidemic among deer, elk and members of the deer

Scientists at Harvard University and the Broad Institute’s Stanley Center for Psychiatric Research have made a major advance in the development of human brain ‘organoids’: miniature, 3-D tissue cultures that model a patient’s own brain cells in a dish. Their new method, published in Nature, consistently grows the same types of cells, in the same

In a landmark study, scientists at Houston Methodist Research Institute discovered what makes white blood cell counts spike in individuals who have high cholesterol, possibly leading to new therapies for heart disease. Led by Longhou Fang, Ph.D., an associate professor in the Center for Cardiovascular Regeneration, and his postdoctoral fellow Qilin Gu, Ph.D., the team

About 40 percent of the affected patients with Huntington’s disease—a neurodegenerative pathology- show depression symptoms, even in early stages before the apparition of the typical motor symptoms of the disease. An altered function of Cdk5 kinase—an essential enzyme in several cell signalling pathways- could explain the physiopathology of the depressive-like behaviour in Huntington’s disease, according

Gastric cancer, also known as stomach cancer, is the fifth most common cause of cancer-related deaths in Europe. Because of the lack of early signs specifically related to the disease, it’s usually only detected at an advanced stage—when treatment is for the most part ineffective. Driven to improve stomach and other cancer survival rates, for

Drugs used to target HER2-positive invasive breast cancer may also be successful in treating women in the first stages of the disease, researchers at The University of Nottingham have discovered. The findings, published in the British Journal of Cancer and led by experts in the University’s School of Medicine, suggest that extending anti-HER2 drugs to

(HealthDay)—With growing concern about mosquito-borne viruses such as Zika, it’s easy to let down your guard when it comes to ticks. But Lyme disease is still a danger, especially in the Northeast and upper Midwest. In fact, it has affected people in almost every state. Lyme disease is spread through the bite of an infected

Sleeping myths debunked: Getting fewer than five hours a night increases risks of heart disease, strokes and early death and alcohol before bed DOESN’T help you nod off, study finds New York University published the study which looked into sleep and health They searched more than 8,000 websites, news reports and publications  Dr Rebecca Robbins

Parents who have five or more children may face a higher risk of heart disease than those who have only one or two keiki, according to new findings by public health researchers in the Myron B. Thompson School of Social Work at the University of Hawaii at Manoa. Researchers led by Sara Hipp, a recent

Patients with lupus, an inflammatory disease in which the body’s immune system attacks its own tissues, are on average seven to nine times more likely to develop heart disease than the general population. Younger women with lupus are 50 times as likely to develop the disease as young women without the disease. The endothelium—the single