Tag: disease

It is known that the onset of Alzheimer’s disease (AD) is associated with the accumulation of Amyloid beta (Aβ) peptides in small molecular clusters known as oligomers. These trigger the formation of so-called ‘neurofibrillary tangles’ within neurons hamper their workings, ultimately causing cell death and so significant cognitive decline. Very large Aβ oligomers which form

Autopsy is often an overlooked source of medical insight which may be hindering advances in cardiovascular medicine, according to new research published in a special issue of the American Heart Association’s journal Circulation. “Autopsy is a source of discovery that informs the way we think about disease systemically,” said Jeffrey E. Saffitz, M.D., Ph.D., co-editor

A team of researchers says it has linked sensitivity to an allergen in red meat to the buildup of plaque in the arteries of the heart. While high saturated fat levels in red meat have long been known to contribute to heart disease for people in general, the new finding suggests that a subgroup of

The results of a study to be presented at the Annual European Congress of Rheumatology (EULAR 2018) suggest that rates of anxiety and depression in patients with rheumatoid arthritis correlate with measures of disease activity over the first year following diagnosis. Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects a person’s joints, causing

Researchers at Baylor College of Medicine and Texas Children’s Hospital have identified unexpected new key players in the development of an early onset form of Parkinson’s disease called Parkinsonism. These key players are ceramides, a family of lipid molecules that are found within cell membranes. The researchers propose that ceramides are the linchpin that connects

The waste-management system of the cell appears to play an important role in the spread of Alzheimer’s disease in the brain. A new study has focused on small, membrane-covered droplets known as exosomes. It was long believed that the main task of exosomes was to rid the cell of waste products. However, the understanding of

Blood flow changes in the brains of children, adolescents and young adults with chronic kidney disease may explain why many face a higher risk of cognitive impairment, according to a study published online in the journal Radiology. Prior research has linked chronic kidney disease, a condition characterized by the loss of kidney function over time,

Prostate cancer breakthrough: New DNA test identifies men who are SIX TIMES more likely to develop the disease Researchers identified 63 new genetic mutations linked to the condition  Combined with over 100 variants known to cause the cancer to make the test One in 100 men carry sufficient numbers of genetic variations to put them

The Good Doctors Guide: Meet the best doctors for gall bladder and learn the cutting-edge treatments for inflammatory bowel disease We have identified the country’s top consultants — as judged by their peers The views of more than 260 consultants across seven specialities are revealed The consultants with the most votes from their peers made

In a study of patients with chronic kidney disease (CKD), persistent substance use—especially of hard illicit drugs—was linked with higher risks of CKD progression and early death. The findings appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). CKD is common in the United States, and affected patients

PAD affects the blood vessels causing them to narrow, therefore restricting the blood flow to the arms, kidneys, stomach, and most commonly, the legs. An estimated 8.5 million people in the United States have peripheral artery disease, affecting approximately 12-20 percent of Americans over 60. Peripheral artery disease is a major risk factor for heart

Researchers from Queen Mary University of London have developed new cell-based technologies which could help improve understanding of the muscle-wasting disease Duchenne muscular dystrophy (DMD) and test potential drugs for the disease. DMD is a genetic disorder causing muscle degeneration and weakness, caused by an absence of the protein dystrophin. DMD usually affects only boys,

Rheumatic heart disease is a disease which shouldn’t exist anymore. Caused by an abnormal immune reaction to Strep A infection of the skin and throat, it’s an entirely preventable condition which, left untreated, can spiral into deadly or debilitating complications including stroke, heart rhythm abnormalities, and heart failure. Left untreated, an abnormal immune reaction to Strep

Among homeless individuals cardiovascular disease remains one of the major causes of death due to challenges in predicting initial risk, limited access to health care and difficulties in long-term management, according to a review published today in the Journal of the American College of Cardiology. In the U.S., roughly 550,000 people are homeless on any

Northwestern Medicine scientists identified a cellular mechanism that leads to neurodegeneration in patients with Parkinson’s disease, according to a study published in Proceedings of the National Academy of Sciences. Dimitri Krainc, MD, Ph.D., chair and Aaron Montgomery Ward Professor of Neurology, was the senior author of the study, which demonstrated a link between defective synaptic

South Asians are more likely to die of heart disease, such as heart attacks and strokes caused by atherosclerosis—the disease process that narrows arteries—than East Asians and non-Hispanic whites living in the United States, according to a new scientific statement from the American Heart Association published in its journal Circulation. The statement provides an overview

Research by physician-scientists at the University of Colorado Anschutz Medical Campus offers hope for improved quality of life for people who rely on intravenous nutrition due to intestinal damage. Karim C. El Kasmi, MD, Ph.D., assistant professor of pediatrics, and Ronald Sokol, MD, professor of pediatrics, are authors of an article in the April 2018

Scientists have developed a lab-based system for studying the most common type of liver disease, paving the way for research into new therapies. The team has devised a way to probe Non-Alcoholic Fatty Liver Disease, which affects up to one in three people, using cells in a dish. Researchers will be able to use the

The number of cases of progressive massive fibrosis, the most severe form of black lung disease, has been increasing dramatically among coal workers and especially younger workers in central Appalachia. These new findings represent the first-ever documentation of this spike and were presented by Kirsten Almberg, research assistant professor of environmental and occupational health sciences

The name of an illness can affect the level of care a person receives. Cancer sufferers experiencing fear and uncertainty may have access to cancer care centres. Donations and bequests enable these centres to offer everything from accessible parking, to wig and beauty services, to comprehensive clinical care. A person with arthritis, on the other