Tag: Key

Monash University researchers have made a breakthrough discovery that could pave the way for the development of novel non-opioid painkillers (analgesics) to safely and effectively treat neuropathic pain. The research was published today in the prestigious journal Nature. Neuropathic pain is a type of chronic pain that can occur if your nervous system is damaged

A KAIST immunology research team found that a specific subtype of macrophages that originated from blood monocytes plays a key role in the hyper-inflammatory response in SARS-CoV-2 infected lungs, by performing single-cell RNA sequencing of bronchoalveolar lavage fluid cells. This study provides new insights for understanding dynamic changes in immune responses to COVID-19. In the

Stroke, a devastating condition that causes damage to the brain due to interruption of blood supply, is often considered an adult disease. But children can experience strokes as well. Sadly, pediatric stroke affects one in every 4,000 newborns and an additional 2,000 older children each year. The most common cause of stroke in children is

(HealthDay)—Primary care physicians have been the largest provider of vaccinations for older individuals, according to a study published online in the July 1 issue of the Annals of Family Medicine. Elizabeth Wilkinson, from the Robert Graham Center for Policy Studies in Family Medicine and Primary Care in Washington, D.C., and colleagues used 2017 Medicare Part

The SARS-CoV-2 virus that causes COVID-19 may have the ability to reactivate dormant tuberculosis (TB). In a novel study, scientists report in The American Journal of Pathology that infection with a specific coronavirus strain reactivated dormant Mycobacterium tuberculosis (MTB) in mice. This knowledge may help to develop new vaccines for COVID-19 and avoid a potential

When Fred VanVleet brings the basketball up the court, the Toronto Raptors guard needs to read the defense and decide his next move while still controlling a continuous flow of movements to keep his dribble alive. Depending on the actions of his teammates, and the opposing defenders, “Steady’ Freddy may have to change plans of

Active or voluntary learning is a major topic in education, psychology, and neuroscience. Over the years, numerous studies have shown that when learning occurs through voluntary action, there is a modulation of attention, motivation and cognitive control that makes the process much more effective. Consequently, memory is benefited. However, although the physiological processes underlying this

Kinks in quickly established new production and distribution supply chains are a major reason why COVID-19 vaccines approved for use in the United States have been sluggish finding their way into people’s arms, says an expert in logistics and supply chains at The University of Alabama in Huntsville (UAH), a part of the University of

Africa is facing an increasing burden of noncommunicable diseases. The lack of physical activity is a risk factor for most of them. Research on physical inactivity trends in Africa is limited. But evidence suggests that as countries undergo transitions such as increased urbanization, physical activity levels may decline. But in Africa, the health agenda is

In breakthrough colon cancer research, scientists at ChristianaCare’s Helen F. Graham Cancer Center & Research Institute have discovered a link between two key signaling pathways crucial to the development and growth of colon cancer. The study is published today in the journal PLOS ONE. The scientists identified the link between the retinoic acid or RA

New research published in Diabetologia (the journal of the European Association for the Study of Diabetes) shows that antibody responses to SARS-CoV-2 are similar in COVID-19 patients with and without diabetes, and thus are unlikely to be responsible for the higher death rates in patients with diabetes. Furthermore, they found that a particular antibody response

To understand how any given disease affects the body, scientists need a wide array of tools. One of the most valuable and indispensable instruments in their toolkit are clinical samples—small amounts of blood, urine, mucus, spit and tissue that can be used to study disease in a patient. Now, a team led by Harvard Medical

Zika virus infection can stunt neonatal brain development, a condition known as microcephaly, in which babies are born with abnormally small heads. To determine how best to prevent and treat the viral infection, scientists first need to understand how the pathogen gets inside brain cells. Employing different approaches to answer different questions, two research teams

A group of researchers at Osaka University revealed that endothelial cell-selective adhesion molecule (ESAM), a surface marker for hematopoietic stem cells (HSCs) and vascular endothelial cells (ECs), played an important role in the ontogeny of hematopoiesis in mice, particularly in the development of adult-type erythropoiesis. Their research results were published in Stem Cell Reports. In

Researchers have cleared a major obstacle in the development of an HIV vaccine, proving in animal models that effective, yet short-lasting antibodies can be coaxed into multiplying as a fighting force against the virus. The finding, led by a team of researchers at the Duke Human Vaccine Institute (DHVI) and Boston Children’s Hospital, publishes online

Why female fertility declines with age: Scientists blame the decay of a protein that acts like a ‘rubber-band’ inside eggs Decay of a protein called cohesin weakens vital structures of chromosomes This is believed to cause an abnormal amount of chromosomes in older eggs Too many or too few chromosomes may lead to failure of the

Toxic algal blooms can be devastating to natural waterways, robbing them of oxygen, creating dead zones, and sickening people and animals. However, they may also be beneficial, potentially helping combat the progression of neurodegenerative disease, a URI College of Pharmacy study is showing. Assistant Professor of Biomedical and Pharmaceutical Sciences Matthew Bertin is teaming up

Scientists at the University of Surrey have discovered that a natural antioxidant commonly found in green tea can help eliminate antibiotic resistant bacteria. The study, published in the Journal of Medical Microbiology, found that epigallocatechin (EGCG) can restore the activity of aztreonam, an antibiotic commonly used to treat infections caused by the bacterial pathogen Pseudomonas

For long-distance transportation within the cell, RNA molecules rely on hitchhiking. A microscopic RNA molecule might need to travel as far as a meter to get from the nucleus of a nerve cell to its tip, where it’s needed to make a protein. But exactly how RNA gets around has been “a long-standing question in

Our teeth take thousands of bites per day, and understanding exactly what holds them in place and how is key to helping people live with their own teeth for longer. Now new research published in the Journal of Dental Research has shed light on the science behind the formation of the periodontal ligament, which helps