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High-risk prostate cancer, that which has continued to grow but not yet metastasized, is commonly treated with combination therapies. Each method has pros and cons, but there is little clarity whether one might be more effective than the other. For the first time, researchers have shown that more patients live longer if treated with the

The emergencies chief for the World Health Organization says insecurity, public defiance about vaccinations and political jockeying could create a “perfect storm” leading Congo’s latest Ebola outbreak to spread. Dr. Peter Salama says the response is at a “critical juncture” in eastern North Kivu province, where the outbreak was declared nearly two months ago. Health

MONDAY, Sept. 24, 2018 — There is variation in the net clinical benefit of anticoagulants based on variation in published atrial fibrillation (AF) stroke rates, according to a study published online Sept. 25 in the Annals of Internal Medicine. Sachin J. Shah, M.D., M.P.H., from the University of California in San Francisco, and colleagues examined

About one decade after its first benefit assessment of negative pressure wound therapy (NPWT), the German Institute for Quality and Efficiency in Health Care (IQWiG) is reassessing this treatment method. However, then as now, its benefit and harm are unclear. Whereas only few studies with very limited informative value were available in 2006, over 100

Disease and infection can alter bodily odor. This mechanism is an important tool, albeit one that we are not usually aware of, in guiding social interactions self-preservation mechanisms. If we can “sense” that a stranger on the bus has a cold, we may instinctively avoid sitting down next to them. Previous research has shown that

Genomic screening of more than 50,000 people shows that more than 80% of those who carry an identifiable genetic risk for breast, ovarian, prostate, and pancreatic cancer don’t know it despite frequent interaction with the healthcare system. The findings were published Sept. 21 in the journal JAMA Network Open. In the absence of routine screening,

A new outbreak of a rare but preventable eye infection that can cause blindness, has been identified in contact lens wearers in a new study led by UCL and Moorfields Eye Hospital researchers. The research team found a threefold increase in Acanthamoeba keratitis since 2011 in South-East England. Reusable contact lens wearers with the eye

An investigation published by The BMJ today raises fundamental questions about the transparency of information surrounding the safety of GlaxoSmithKline’s Pandemrix vaccine used in 2009-2010. Eight years after the 2009 H1N1 “swine flu” outbreak, new information is emerging of a striking difference in the number and frequency of adverse events reported for three GSK pandemic

Premenopausal women who have their ovaries surgically removed face an increased risk of developing chronic kidney disease, according to a Mayo Clinic study published on Wednesday, Sept. 19, in the Clinical Journal of the American Society of Nephrology. “This is the first study that has shown an important link between estrogen deprivation in younger women

(HealthDay)—There are substantial disparities in the geographic distribution of dermatologists that are worsening with time, according to a study published online Sept. 5 in JAMA Dermatology. Hao Feng, M.D., from New York University in New York City, and colleagues analyzed county-level data (1995 to 2013) from the Area Health Resources File to evaluate the longitudinal

Many people have excess fat and low muscle tone in the upper arms. A person may notice the skin in this area starting to wobble or droop. Some people refer to this as having “bat wings.” The main muscles in the upper arm are the triceps and biceps. The biceps are at the front of

Low-income Michigan residents who enrolled in a new state health insurance plan didn’t just get coverage for their health needs—many also got a boost in their financial health, according to a new study. People who gained coverage under the state’s expanded Medicaid program have experienced fewer debt problems and other financial issues than they had

Patients using inhaled steroids to control asthma and other breathing problems may be at greater risk for developing nontuberculous mycobacteria (NTM) lung infections, according to new research published online in the Annals of the American Thoracic Society. NTM are in the same family as tuberculosis, but NTM come in many different species and are widely

Researchers at St. Jude Children’s Research Hospital have created a massive database of the changes in gene activity of individual cells in the cerebellum during embryonic development and immediately after birth. The analysis of thousands of brain cells isolated from mice offers researchers a high-resolution map that enables scientists to view the detailed genomic changes

In a study into the sexual orientation and gender identity development of thousands of youth across the nation, a San Diego State University team found that about 1 percent of 9 and 10-year old children surveyed self-identified as gay, bisexual or transgender. As the majority of studies indicate that lesbian, gay, bisexual and transgender (LGBT)

(HealthDay)—A total of 43,371 new cases of human papillomavirus (HPV)-associated cancers were reported in 2015, with oropharyngeal squamous cell carcinoma (SCC) being the most common HPV-associated cancer, according to research published in the Aug. 24 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report. Elizabeth A. Van Dyne, M.D.,

TUESDAY, Sept. 11, 2018 — Many outpatient opioid prescriptions have no documented medical indication, according to a research letter published online Sept. 11 in the Annals of Internal Medicine. Tisamarie B. Sherry, M.D., Ph.D., from the RAND Corporation in Boston, and colleagues examined the percentage of opioid prescriptions with a documented medical indication between 2006

Researchers from the University of Luxembourg have discovered a molecular mechanism that is responsible for the spread of cancer cells in the body and the development of metastases in patients with colon cancer. Their findings could help to develop treatments that inhibit tumor growth. Colorectal cancer (CRC) is among the most prevalent cancer types worldwide,

Mononuclear phagocytes can both promote and inhibit inflammation. An LMU team has now shown that individual phagocytes in the central nervous system can play both roles, sequentially adopting different phenotypes with distinct functions. Mononuclear phagocytes, which recognize, engulf and digest damaged and infected cells, form an important arm of the innate immune system. However, they

High blood pressure rates could nearly double in women of childbearing age if the latest guidelines are used, according to a new study. But researchers say more investigation is needed to see if those lower blood pressure targets in pregnant women are safe—or effective. The study, published Sept. 10 in the journal Hypertension, set out