A growing number of drugs are being approved on the basis of indirect (‘surrogate’) measures that do not always reliably predict outcomes that matter most to patients, such as living longer or feeling better. In The BMJ today, experts argue that surrogate endpoints provide no guarantee of clinical benefit and should be used only as
As a medical student working with Alberta Health Services to vaccinate people against COVID-19, I have been asked my fair share of questions about the COVID-19 vaccines—from the need for booster doses to rare side effects. A few days ago, I told an individual who was about to receive her second dose of the Moderna
What can I do about my burning mouth that I’ve had for years? DR MARTIN SCURR answers your health questions I’ve suffered from burning mouth syndrome for about 25 to 30 years. No one seems to be able to help. I am 78 years old. Can you suggest anything? Margaret Wheddon, via email. Burning mouth
For all the pomp surrounding fast food “plant-based” burgers and breakfast sandwiches, you might not think that McDonald’s next move would be to release not one, but three, new chicken sandwiches. Yet they’ve done so today, and, to say the least, McDonald’s is HYPED. They’ve been working on their new creation for “years,” according to
When Narayan Mitra died on July 16, a day after being admitted to the hospital for fever and breathing difficulties, his name never appeared on any of the official lists put out daily of those killed by the coronavirus. Test results later revealed that Mitra had indeed been infected with COVID-19, as had his son,
A lot to think about! Nikki Bella worried about how well she knew her fiancé, Artem Chigvinstev, after her negative pregnancy test results. “I don’t even know what Artem’s beliefs are with kids,” the Total Bellas star, 36, said during a Thursday, May 14, confessional on the E! show. “That would freak me out. All
Several clinical trials have reported beneficial effects of organic nitrates on bone health, which could lead to a reduced risk of fractures. Some of these trials have been retracted because of scientific misconduct; however. A new study published in the Journal of Bone and Mineral Research found that organic nitrates do not have clinically relevant
Sleep is one of those things that’s necessary for absolutely everybody, while also being pretty hard to understand to understand or find for some. Insomnia is an ever-present spectre for some, while conditions like sleep paralysis, sleep apnea, severe snoring, or night terrors pervade the lives of others. Given that sleep can affect everything from
Love can make us do crazy things. It often prompts us to behave in counterintuitive ways, like, for example, placing the wellbeing of our loved ones above our own. But why? Such altruism has perplexed and intrigued scientists for centuries. A new study out of UC Santa Barbara explores how an individual’s genetics and brain
An investigation published by The BMJ today raises fundamental questions about the transparency of information surrounding the safety of GlaxoSmithKline’s Pandemrix vaccine used in 2009-2010. Eight years after the 2009 H1N1 “swine flu” outbreak, new information is emerging of a striking difference in the number and frequency of adverse events reported for three GSK pandemic
The beginning of the school year can be overwhelming. There will be shopping for supplies, packing lunches and planning that all-important first-day-of-school outfit — by the time you meet your kid’s teacher, your brain may be running on empty. Here are 10 questions you should ask to start this year off on the right foot.
Pin For a lot of parents, their back-to-school routines include school supply shopping, looking up recipes for healthy lunches and scheduling a pediatric checkup for their kids. As long as we get some face time with our children’s doctor, we want to be prepared with knowledge going in so we utilize our time and ask
‘How do I prevent sore nipples and is my child getting enough milk?’: Experts reveal the answers to the top 10 breastfeeding questions new mothers ask Alexa ‘Is my child getting enough milk?’ is the number one question mothers ask In second place, breastfeeding mothers query ‘why is my child crying?’ Public Health England has
In the last week we’ve witnessed the deaths by suicide of two high-profile figures – Kate Spade and Anthony Bourdain. Both seemed to have the world at their feet – loved, supported, sought-after, wealthy and admired. Both deaths came as a complete shock to those who knew them best.How can two famous people, with every
ASK THE GP: Why have I had a cold for 12 years? Dr Martin Scurr answers your questions Since I was 11 years old, I’ve had what appears to be a chronic cold. I sneeze continuously and it weakens me and gives me itchy eyes and pains in my face. I’m now 23 and there
‘Is using a crisp packet between my teeth better than floss?’ Dentists reveal the 9 strangest questions ever asked by patients Thirty UK dentists were quizzed about some of questions they have been asked They include one confused patient wondering if it is safe to eat dental floss Another asked why they have to brush
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