In recent years, targeted therapies have cemented their place as some of the most important tools in cancer treatment. These medicines are designed to block specific signals that tumor cells use to grow and spread, while at the same time leaving normal cells unharmed. Targeted therapies can significantly extend patients’ lives, but the benefits are
A new genetic risk factor for Motor Neurone Disease (MND), which if treated could halt or prevent the degenerative condition, has been identified in so-called ‘junk DNA’ by scientists at the University of Sheffield. The newly discovered genetic changes are present in up to one percent of MND patients. The pioneering research, published in the
Patients with locally advanced cervical cancer benefit significantly from an innovative radiotherapy technique co-developed by MedUni Vienna under the direction of Richard Pötter and Christian Kirisits. The technique provides better tumor control and produces fewer side-effects. This is substantiated by the results of the prospective, international, multi-center study, EMBRACE I, conducted under the direction of
Many cancer researchers can claim to have devised “smart bombs.” What has been missing is the stealth bomber—a delivery system that can slip through the body’s radar defenses. Oncolytic viruses, or viruses that preferentially kill cancer cells, have been discussed and tested for decades. An oncolytic virus against melanoma was approved by the FDA in
Researchers from the Faculty of Health and Sport Sciences at the University of Tsukuba studied the way blind players and sighted non-athletes tracked an incoming noise-making ball. They found that blind players employed a larger downward head rotation when trapping the rolling ball, compared with blindfolded sighted volunteers. This work may help explain the methods
A gene known for helping facilitate communication between neurons in the nervous system has been discovered to be connected with Alzheimer’s dementia and cognitive decline, according to a national research team led by The Jackson Laboratory and University of Maine. Catherine Kaczorowski, associate professor and Evnin family chair in Alzheimer’s research at The Jackson Laboratory
The NordicMathCovid project aims to model corona and future epidemics more extensively than has been previously attempted. It also builds towards long-term cooperation in mathematical modeling and extensive collection of health data. “One of the purposes of the project is to compare different corona models and scenarios in different countries. For example, we can apply
Menarini Silicon Biosystems has announced the publication of a research study providing support for the reliability of using circulating tumor cell (CTC) count to guide frontline therapy choice for patients with estrogen receptor-positive (ER+), HER2-negative (HER2) metastatic breast cancer. Published in the November issue of JAMA Oncology, this is the first study to support clinical
When antibody-producing immune cells encounter infectious pathogens for the first time, they engage a signal cascade to generate a massive activation signal within seconds. The mechanisms underlying this acute initial activation have not been fully understood. In a new study by Yale Cancer Center, scientists have identified the short endosomal protein interferon-inducible transmembrane protein 3
When you are faced with a choice — say, whether to have ice cream or chocolate cake for dessert — sets of brain cells just above your eyes fire as you weigh your options. Animal studies have shown that each option activates a distinct set of neurons in the brain. The more enticing the offer,
A statistical estimation technique developed by a University of Notre Dame researcher offers public health officials a new way to build short-term forecasts of coronavirus diagnoses and deaths. It also provides additional insight into the effectiveness of earlier pandemic mitigation measures in 30 countries. As the COVID-19 pandemic began to spread globally in early 2020,
Are the potentially crippling side-effects of new cancer ‘wonder drugs’ worth the risk? Patients with otherwise untreatable tumours benefiting from immunotherapy The treatment costs around £100,000 per patient per year, and has side-effects One in ten patients given immunotherapy for cancer suffer rheumatoid arthritis Surviving cancer against the odds can give patients a new lease
FRIDAY, Oct. 16, 2020 (American Heart Association News) — Chanel Davis-Mitchell and her husband, Benji Mitchell, were looking forward to parenthood after the birth of their healthy baby boy, Braxton. Despite a high-risk pregnancy and a massive amount of fluid weight Chanel gained during the final two months, doctors assured her all would be fine
Researchers at the Netherlands Cancer Institute have discovered salivary glands in a previously unknown location. This is potentially great news for patients with head and neck tumors: Radiation oncologists will now be able to circumvent this area to avoid potential complications. The research is forthcoming in Radiotherapy & Oncology. Advanced technology allows scientists to visualize
An Edith Cowan University (ECU) study has revealed that a key blood marker of cancer could be used to select the most effective treatment for melanoma. The discovery, which has the potential to improve melanoma survival rates, was published today in Clinical Cancer Research, a journal of the American Association for Cancer Research. The research
A new study from the University of Aberdeen and the University of Bath has found the optimal age at which sense of touch and hearing best work together to compensate for blindness. The research led by Dr. Meike Scheller from the University of Aberdeen found that blindness before the age of eight or nine facilitates
Babies born to mothers who smoked during pregnancy are more likely to suffer from impaired lung development. They are also more susceptible to developing lung diseases such as asthma and chronic obstructive pulmonary disease (COPD), according to a new research article published in the American Journal of Physiology-Lung Cellular and Molecular Physiology. The article has
Is this person with chest pain having a heart attack? That’s a question EMTs frequently confront when responding to 911 calls. A study conducted at Wake Forest Baptist Health shows that on-scene use of a new protocol and advanced diagnostic equipment can help paramedics better identify patients at high risk for adverse cardiac events. This
The Czech Republic registered a record high of 3,130 new COVID-19 cases on Thursday, reaching in 24 hours a figure comparable with the entire month of March, health ministry data showed Friday. It was the third straight daily record for the EU member of 10.7 million people, which has registered 44,155 confirmed cases and 489
A Rutgers-led team has created a smart drug delivery system that reduces inflammation in damaged nervous tissues and may help treat spinal cord injuries and other neurological disorders. The system, which uses extremely thin biomaterials implanted in the body, also protects nerve fibers (axons) that connect nerve cells in injured neural tissues, according to a
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