Tag: of

Evening use of light-emitting tablets may disrupt healthy sleep

A new Physiological Reports study reveals that evening use of light-emitting tablets can induce delays in desired bedtimes, suppress secretion of melatonin (the hormone that regulates sleep and wakefulness), and impair next-morning alertness. Nine healthy adults participated in a randomized and counterbalanced study comparing 5 consecutive evenings of unrestricted use of light-emitting tablet computers versus

Surveillance intensity not associated with earlier detection of recurrence or improved survival in colorectal cancer

A national retrospective study led by researchers at The University of Texas MD Anderson Cancer Center found no association between intensity of post-treatment surveillance and detection of recurrence or overall survival (OS) in patients with stage I, II or III colorectal cancer (CRC). Published in the Journal of the American Medical Association, the study is

Researchers discover novel mode of neurotransmitter-based communication

Researchers at the University of California, Irvine School of Medicine have discovered the first example of a novel mode of neurotransmitter-based communication. The discovery, published in Nature Communications, challenges current dogma about mechanisms of signaling in the brain, and uncovers new pathways for developing therapies for disorders like epilepsy, anxiety and chronic pain. Voltage-gated potassium

Molecular basis for varied presentations of ETEC explored

(HealthDay)—The EtpA adhesion molecule, which is secreted by enterotoxigenic Escherichia coli (ETEC) strain H10407, is a dominant ETEC blood group A-specific lectin/hemagglutinin, according to a study published online May 17 in the Journal of Clinical Investigation. Pardeep Kumar, Ph.D., from the Washington University School of Medicine in St. Louis, and colleagues examined the molecular basis

Breath test shows promise for diagnosis of esophagogastric CA

(HealthDay)—Breath analysis shows potential for noninvasive diagnosis of esophagogastric cancer (OGC), according to a study published online May 17 in JAMA Oncology. Sheraz R. Markar, Ph.D., from Imperial College London, and colleagues recruited patients for a diagnostic validation study conducted at three London hospital sites. A total of 335 patients were included: 172 in the

New guidelines may slightly increase reliability, accuracy of melanoma diagnoses

In a new study, researchers have developed updated guidelines for classifying a serious form of skin cancer called invasive melanoma. The American Joint Committee on Cancer, an organization that provides information on “cancer staging,” or the severity of individual cases of cancer, recently updated its guidelines for melanoma. The researchers found that when pathologists used

Ozone exposure at birth increases risk of asthma development

A long-term study of the health of Canadian children has found that exposure to ozone (O3), a common air pollutant, at birth was associated with an 82 percent increased risk of developing asthma by age three. The study, which was a 10-year follow-up to the 2006 Toronto Child Health Evaluation Questionnaire (T-CHEQ), was presented at

MR spectroscopy imaging reveals effects of targeted treatment of mutant IDH1 gliomas

Using a novel imaging method, a Massachusetts General Hospital (MGH) research team is investigating the mechanisms behind a potential targeted treatment for a subtype of the deadly brains tumors called gliomas. In their report published in Nature Communications, the researchers describe using magnetic resonance spectroscopy (MRS) imaging—which reflects metabolic rather than structural aspects of tissues—to

IgG antibodies activate blood platelets and contribute to the severity of anaphylaxis

The most severe allergic reaction, anaphylaxis (or anaphylactic shock), is the result of an inappropriate immune reaction following the introduction of a usually harmless antigen into the body. The production of antibodies against this antigen (or allergen) allows the formation of antibody-antigen complexes that trigger a massive secretion of potent mediators, resulting in organ failure,

The accidental discovery of stem cells

Till knows of what he speaks; it was almost 60 years ago that the renowned University of Saskatchewan graduate, along with a colleague, found something unexpected in research results that simply could not be ignored. Although they did not know it at the time, the two scientists were on the path to discovering stem cells