Tag: survival

Researchers from the Departments of Cell Biology and Medical Physiology at the University of Seville have identified that a high expression of the human protein VRK1 is associated with tumor aggressiveness and low survival among neuroblastoma patients. Aggressive neuroblastoma is one of the most common solid childhood cancers and causes disproportionately high mortality in affected

TUESDAY, Dec. 8, 2020 — Self-reported patient race is the most important factor associated with poorer survival in patients with acute myeloid leukemia (AML), according to a study presented at the annual meeting of the American Society of Hematology, held virtually from Dec. 5 to 8. Bhavana Bhatnagar, D.O., from The Ohio State University Comprehensive

Patients with locally advanced cervical cancer benefit significantly from an innovative radiotherapy technique co-developed by MedUni Vienna under the direction of Richard Pötter and Christian Kirisits. The technique provides better tumor control and produces fewer side-effects. This is substantiated by the results of the prospective, international, multi-center study, EMBRACE I, conducted under the direction of

Signals from two key proteins are essential for the survival of our ‘immunological memory’, according to new research from scientists at the Francis Crick Institute, published in the Journal of Experimental Medicine. Memory B cells are long-lived cells that confer immunological memory by providing rapid and robust antibody responses to infections our body has seen

Patients with low income have a higher risk of death following surgery for lung cancer compared with patients with high income. The association remains even after taking prevalence of common comorbidities, and other factors that are known to influence the risk of death, into account. This is according to a study published in the journal

Patients with acutely life-threatening health conditions who were treated in the innovative Critical Care Resuscitation Unit (CCRU) received faster treatment and had better health outcomes, including a 36 percent lower risk of dying than those who were transferred from a hospital’s emergency department then evaluated and treated in a traditional intensive care unit, according to

(HealthDay)—Young, low-income patients with bone or soft tissue sarcomas have decreased overall survival (OS), regardless of disease stage at presentation, according to a study published online Dec. 15 in Cancer Medicine. Neela L. Penumarthy, M.D., from Seattle Children’s Hospital, and colleagues used data from the University of California San Francisco Cancer Registry to identify patients

Researchers from The University of Texas MD Anderson Cancer Center today reported results from a pooled analysis of more than 5,100 breast cancer patients that found residual cancer burden (RCB) continuous index and classification were independently and strongly prognostic for all breast cancer phenotypes. The study’s results were presented by W. Fraser Symmans, M.D., professor

Colon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to adapt to the lack of oxygen and nutrients inside the tumor. Statins, which are often prescribed to lower cholesterol, block this metabolic pathway and cause the cancer cells to die, as scientists from

Air pollution slashes the survival chances for heart transplant patients, finds study Experts at Case Western Reserve University in Ohio tracked 22,000 people All of the patients had received a donor heart between 2004 and 2015  They compared patients’ home address against levels of PM2.5 pollution  Air pollution slashes the survival chances for people who

A shift in surgical practice over the last decade towards the earlier removal of a type of slow-growing but ultimately fatal brain tumor has led to dramatic improvements in survival and seizure control for patients, a study at UCLH and UCL has found. Patients with low-grade gliomas (LGGs) had a 50 percent chance of dying

Researchers recently produced an algorithm that could guess whether heart patients had lived or died from their condition within a year. By looking at data from a test of the heart’s electrical activity known as an electrocardiogram or ECG, the algorithm successfully predicted patient survival in 85% of cases. But its developers couldn’t explain how

Using cells from human breast cancers and mouse breast cancer models, researchers at the Johns Hopkins Kimmel Cancer Center say they have significant new evidence that tumor cells exposed to low-oxygen conditions have an advantage when it comes to invading and surviving in the bloodstream. The experiments mapping the “fate” of the cells in two-

The checkpoint inhibitor pembrolizumab (Keytruda) increases the survival time of patients with advanced head and neck cancers, according to a new global study led by Yale Cancer Center (YCC). The data was published today in the journal The Lancet. The findings of the phase 3 study show that, compared to the standard therapy, overall survival

The standard of care for women with stage III/IVA endometrial cancer following surgery has been chemotherapy and radiation to prevent recurrence. But in a surprising new finding, radiation combined with chemotherapy did not increase recurrence-free survival in these women, reports a National Cancer Institute-sponsored Gynecology Oncology Group study led by a Northwestern Medicine scientist/physician. This

Researchers from Queen Mary University of London studied the effectiveness of one of the largest ever national quality improvement programmes in the National Health Service (NHS) and found no improvement in patient survival. The overall risk of death after inpatient surgery within the NHS is one in 65. However, one in ten patients undergoing emergency

Surgery was associated with higher survival rates for patients with HER2-positive (HER2+) stage 4 breast cancer compared with those who did not undergo surgery, according to results presented at the AACR Annual Meeting 2019, March 29-April 3. Between 20 and 30 percent of all newly diagnosed stage 4 breast cancer cases are HER2+, explained the

The first and most distinct consequence of daily mild stress is an increase in rapid-eye-movement (REM) sleep, a new study in the journal PNAS reports. The research also demonstrated that this increase is associated with genes involved in cell death and survival. REM sleep, also known as paradoxical sleep, is the sleep state during which

TUESDAY, Nov. 6, 2018 — There were significant improvements in one-year survival among patients with end-stage renal disease (ESRD) initiating dialysis following Medicaid expansion with the Affordable Care Act, according to a study published online Oct. 25 in the Journal of the American Medical Association. Shailender Swaminathan, Ph.D., from the Brown University School of Public

(HealthDay)—Cancer treatment is associated with a clinically meaningful survival benefit in older, medically complex patients with superficial bladder cancer (SBC), according to a study published online Oct. 5 in Cancer. Tullika Garg, M.D., M.P.H., from Geisinger in Danville, Pa., and colleagues evaluated the association between treatment of SBC and 10-year mortality in 1,800 medically complex